Systemic Anti Cancer Therapy Protocols

These clinical protocols have been developed by local clinicians, with the support of the South West Clinical Network (SWCN). The information is provided as guidance only, and has no legal or official standing. The guidance does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of each patient, in consultation with the patient and/or their guardian or carer. Availability of treatments may change, subject to NHS funding agreements. These protocols must be used in conjunction with local and national commissioning guidance.

The protocols are still being updated and more will be added to this website as they are completed. If you have any queries or suggestions, or would like to be involved in the development of these protocols please contact us

NEWSFLASH! WE HAVE A NEW WEBSITE. THE  PROTOCOL SECTION CAN BE FOUND HERE: https://www.swagcanceralliance.nhs.uk/protocols/

Please familiarise yourself with this website, as the SWCN website will be deactivated on Wednesday 31st March 2021.

The protocols are listed alphabetically and can be filtered by cancer site, for example, by selecting Haematology, Leukaemia, Acute Lymphocytic Leukaemia, to access the relevant list.

A button named ‘Reset’ needs to be pressed to search for a different list of protocols.

Oncology

ALERT: INTERIM TREATMENT CHANGE OPTIONS DURING THE COVID-19 PANDEMIC

https://www.nice.org.uk/guidance/ng161

https://www.esmo.org/guidelines/cancer-patient-management-during-the-covid-19-pandemic

CLINICAL_PRIORITISATION_CANCER_TREATMENT_COVID-19_PANDEMIC_FINAL

Cancer of Unknown Primary

The site specific chemotherapy protocols on the SWCN website can be used for CUP patients, as agreed by the CUP MDT.

The most frequently used protocols are listed below​:
Carboplatin and Etoposide (SCLC) (as per Lung Cancer Protocol)
Carboplatin and Paclitaxel (as per Gynae Cancer protocol)
Gemcitabine and Capecitabine (pancreas) (as per Upper GI protocol)
Gemcitabine and Carboplatin (as per Lung Cancer protocol)
Epirubicin, Cisplatin and Capecitabine (ECX – oesophagus) (as per Upper GI protocol)
Epirubicin, Oxaliplatin and Capecitabine (EOX – oesophagus) (as per Upper GI protocol)
Paclitaxel weekly (as per Gynae protocol)

Haematology

Supportive Therapy

Bone Protection Myeloma 2020
Denosumab
Zoledronic Acid

Guidelines

Bone Protection Myeloma 2020

Archived Protocols

Carboplatin, Gemcitabine and Bevacizumab
Docetaxel, Doxorubicin and Cyclophosphamide (TAC)
Lapatinib and Capecitabine
Topotecan